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RECRUITING
NCT06128304
NA

ACCESS: Accelerating Cervical Cancer Elimination Through the Integration of Screen-and-treat Services

Sponsor: University of California, San Diego

View on ClinicalTrials.gov

Summary

While there has been a significant increase in the uptake of antiretroviral therapy among women living with HIV (WLHIV) in many low- and-middle income countries (LMICs), the coverage of cervical cancer screening and treatment (CCST) among WLHIV remains low. This study aims to leverage the available infrastructure for HIV care and treatment programs in Nigeria to integrate cervical cancer screening and treatment and conduct a cluster randomized, hybrid type III trial design to assess the comparative effectiveness of a Core set of implementation strategies versus a Core+ (enhanced) set of implementation strategies to implement cervical cancer screening, onsite treatment, referral and referral completion, treatment, and retention in care among WLHIV. The overarching goal is to improve the health and life expectancy of WLHIV with co-occurring cervical cancer.

Key Details

Gender

FEMALE

Age Range

25 Years - 64 Years

Study Type

INTERVENTIONAL

Enrollment

2436

Start Date

2023-11-13

Completion Date

2027-08-31

Last Updated

2026-02-10

Healthy Volunteers

No

Interventions

OTHER

Core Implementation strategies

Core Implementation Strategies 1. Ongoing consultation 2. Educational meetings 3. Strengthen referral system 4. Prepare patients to be active participants

OTHER

Core+ Enhanced Implementation Strategies

Includes all of the Core implementation strategies and adds: 5\. Community engagement using Health Beginning Initiative Model 6\. Smart Cards to facilitate patient engagement

Locations (2)

UC San Diego

La Jolla, California, United States

University of Nigeria, Nsukka

Enugu, Enugu State, Nigeria