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rTMS Treatment of Spasticity in Children With Cerebral Palsy/ Hemiplegia Due to ABI - a RCT
Sponsor: The University of Hong Kong
Summary
This RCT aims to investigate the effect of repetitive transcranial magnatic stimulation (rTMS) in treating children with hemiplegoc cerebral palsy. The study will measure any improvement in spasticity after using contra-lesional inhibitory rTMS follow by intensive limb training. Participants will attend a 10-day rTMS treatment sessions, follow by intensive training of the impaired limb. They will also undergo MRI scans before and after the treatment to investiagte the underlying neurophysiological mechanisms that lead to changes clinically by using TMS as well as MR-DKI. Researchers will compare the intervention group and the sham group to see if rTMS could result in improvement of participants' spasticity.
Official title: Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Spasticity in Children With Hemiplegic Cerebral Palsy/ Hemiplegia Due to Acquired Brain Injury - a Randomized Controlled Trial
Key Details
Gender
All
Age Range
7 Years - 18 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2024-01-13
Completion Date
2026-08
Last Updated
2026-04-02
Healthy Volunteers
No
Conditions
Interventions
Repetitive Transcranial Magnetic Stimulation
1 Hz rTMS treatment for 20 mins, follow by 30 mins intensive limb training
Sham Repetitive Transcranial Magnetic Stimulation
Sham Hz rTMS treatment for 20 mins, follow by 30 mins intensive limb training
Locations (1)
Li Ka Shing Faculty of Medicine
Hong Kong, Hong Kong, Hong Kong