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Intermittent ADVOS vs. Hemodialysis in Non-intensive Care Patients With Liver Dysfunction
Sponsor: University Medical Center Mainz
Summary
In the planned randomized controlled prospective pilot study, we aim to evaluate ADVOS compared with conventional hemodialysis regarding the elimination of protein-bound toxins in patients with therapy-refractory hepatorenal syndrome. The study will be performed in a regular non-ICU ward with a large experience in the use of the ADVOS therapy.
Official title: Prospective Randomized Controlled Trial for Protein-bound Toxins Removal With Intermittent ADVOS vs. Hemodialysis Treatment in Non-intensive Care Patients With Pre-existing Liver Dysfunction and Indication for Extracorporeal Renal Support. The ADVOMITTENT Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
14
Start Date
2023-06-01
Completion Date
2026-06-01
Last Updated
2023-11-13
Healthy Volunteers
No
Interventions
Hemodialysis
5 treatments with hemodialysis on day 1, 2, 3, 5 and 7
ADVOS
5 treatments with ADVOS on day 1, 2, 3, 5 and 7
Locations (1)
UNIVERSITÄTSMEDIZIN der Johannes Gutenberg-Universität Mainz I. Medizinische Klinik und Poliklinik
Mainz, Rhineland-Palatinate, Germany