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Endurance Exercise & Virtual Reality for Optimizing Cortical Excitability and Neuroplasticity in PD
Sponsor: The University of Texas Health Science Center at San Antonio
Summary
This study aims to determine the effects of aerobic exercise as a primer to add-on virtual reality (VR)-based rehabilitation on balance, postural control and neuroplasticity (ability of brain to adapt in structure and function) in individuals with Parkinson's disease (PD). This study will utilize two groups - one group will receive the exercise and VR, while the other group will receive stretching exercise and VR over eight weeks. The study team will administer outcomes at baseline, post-intervention (8 weeks) and follow-up (6 weeks after post-assessment).
Official title: High Intensity Endurance Exercise as a Primer to Virtual Reality for Optimizing Cortical Excitability and Neuroplasticity in Parkinson's Disease (PD)
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
16
Start Date
2024-02-09
Completion Date
2026-12-31
Last Updated
2026-03-31
Healthy Volunteers
No
Conditions
Interventions
High intensity endurance exercise
High intensity interval exercise on a recumbent stepper for 30 minutes, 3 days per week.
Stretching exercise
Stretches of face, neck, upper extremity, trunk and lower extremity muscles including whole body stretches for 30 minutes, 3 days per week.
Virtual reality (VR)-based gaming
VR games will involve games that challenge balance such as reaching different targets during activities such as sit to stand, dodging obstacles etc. Participants will play approximately 6 games for 30 minutes, 3 days a week.
Locations (1)
UT Health San Antonio- Dept. of Physical Therapy
San Antonio, Texas, United States