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Fortified Oral Rehydration Therapy for Pediatric Diarrhea
Sponsor: Paul A Breslin
Summary
The goal of this clinical trial is to compare amino acid-fortified oral rehydration therapy (ORT) to the standard of care ORT in pediatric patients with acute gastroenteritis (AGE). The main questions it aims to answer are: * can amino acid-fortified ORT reduce the duration and severity of AGE compared to standard of care ORT? * can amino acid-fortified ORT increase the secretion of antimicrobial peptides in the gastrointestinal tract compared to standard of care ORT? Participants will be assigned to the experimental treatment (amino acid-fortified ORT) or the standard of care ORT and their disease severity, duration, and stool antimicrobial peptide content.
Official title: Reduction of Severity and Duration of Pediatric Gastroenteritis Through Amino Acid Fortified Oral Rehydration Therapy
Key Details
Gender
All
Age Range
6 Months - 5 Years
Study Type
INTERVENTIONAL
Enrollment
72
Start Date
2024-06-01
Completion Date
2027-06
Last Updated
2026-02-12
Healthy Volunteers
No
Conditions
Interventions
Fortified Oral Rehydration Therapy
Oral rehydration solution with reduced glucose and added amino acids.
Standard of Care Oral Rehydration Therapy
Glucose-based oral rehydration therapy according to World Health Organization guidelines.
Locations (1)
Robert Wood Johnson University Hospital
New Brunswick, New Jersey, United States