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RECRUITING
NCT06138964
PHASE2

Comparing the Effect of siSPARC Microneedle Patch Versus siSPARC+siLR4A Microneedle Patch on Post-surgical Scars

Sponsor: National Skin Centre

View on ClinicalTrials.gov

Summary

This randomized, double-blind controlled study aims to compare the effect on appearance of post- surgical scars between daily application of siSPARC microneedle patch versus siSPARC + siLR4A microneedle patches. These are patches comprising short microneedles embedded with hydrolysed RNA (siRNAs).

Official title: Randomized Intra-individually Controlled Double-blinded Trial Comparing Effect of Small Interfering RNA Against SPARC (siSPARC) Microneedle Patch Versus Small Interfering RNA Against SPARC and IL4-RA (siSPARC + siLR4A) Microneedle Patch on Appearance of Post-surgical Scars

Key Details

Gender

All

Age Range

21 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2023-11-14

Completion Date

2024-11-14

Last Updated

2024-06-24

Healthy Volunteers

Yes

Interventions

DRUG

siSPARC + siLR4A microneedle patches

siSPARC + siLR4A microneedle patch

DRUG

siSPARC microneedle patch

siSPARC microneedle patch

Locations (1)

National Skin Centre

Singapore, Singapore