Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT06139627
NA

Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy

Sponsor: City of Hope Medical Center

View on ClinicalTrials.gov

Summary

This clinical trial tests how well a geriatric assessment (GA) with GA-directed treatment recommendations, compared to GA with usual care, works in identifying risk factors, reducing chemotherapy radiation toxicity and functional decline, and improving the overall quality of life in older patients with non-small cell lung cancer (NSCLC). Older patients with lung cancer undergoing chemotherapy are at an increased risk of adverse outcomes including treatment toxicity and functional and physical consequences. This makes it very challenging for the physicians to balance the benefits against the risk of chemotherapy in older cancer patients. A geriatric assessment may be useful in identifying risk factors for chemotherapy radiation toxicity. Communicating these geriatric assessment findings and assessment-based recommendations to a patient's treating physicians may help them make more informed decisions about treatment options for patients. Making treatment decisions using GA-based recommendations may reduce adverse events and improve outcomes in patients receiving treatment for NSCLC.

Official title: Geriatric Assessment and Management (GAM) for Older Adults With Non-Small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy (GAM-CRT)

Key Details

Gender

All

Age Range

60 Years - Any

Study Type

INTERVENTIONAL

Enrollment

180

Start Date

2024-05-21

Completion Date

2026-07-19

Last Updated

2025-07-04

Healthy Volunteers

Yes

Interventions

OTHER

Best Practice

Receive usual care

PROCEDURE

Biospecimen Collection

Undergo blood and stool sample collection

OTHER

Communication Intervention

Receive GA assessment summary and assessment-based recommendations

OTHER

Comprehensive Geriatric Assessment

Complete GA

OTHER

Electronic Health Record Review

Ancillary studies

OTHER

Survey Administration

Ancillary studies

Locations (3)

City of Hope Medical Center

Duarte, California, United States

University of Rochester

Rochester, New York, United States

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, United States