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Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy
Sponsor: City of Hope Medical Center
Summary
This clinical trial tests how well a geriatric assessment (GA) with GA-directed treatment recommendations, compared to GA with usual care, works in identifying risk factors, reducing chemotherapy radiation toxicity and functional decline, and improving the overall quality of life in older patients with non-small cell lung cancer (NSCLC). Older patients with lung cancer undergoing chemotherapy are at an increased risk of adverse outcomes including treatment toxicity and functional and physical consequences. This makes it very challenging for the physicians to balance the benefits against the risk of chemotherapy in older cancer patients. A geriatric assessment may be useful in identifying risk factors for chemotherapy radiation toxicity. Communicating these geriatric assessment findings and assessment-based recommendations to a patient's treating physicians may help them make more informed decisions about treatment options for patients. Making treatment decisions using GA-based recommendations may reduce adverse events and improve outcomes in patients receiving treatment for NSCLC.
Official title: Geriatric Assessment and Management (GAM) for Older Adults With Non-Small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy (GAM-CRT)
Key Details
Gender
All
Age Range
60 Years - Any
Study Type
INTERVENTIONAL
Enrollment
180
Start Date
2024-05-21
Completion Date
2026-07-19
Last Updated
2025-07-04
Healthy Volunteers
Yes
Interventions
Best Practice
Receive usual care
Biospecimen Collection
Undergo blood and stool sample collection
Communication Intervention
Receive GA assessment summary and assessment-based recommendations
Comprehensive Geriatric Assessment
Complete GA
Electronic Health Record Review
Ancillary studies
Survey Administration
Ancillary studies
Locations (3)
City of Hope Medical Center
Duarte, California, United States
University of Rochester
Rochester, New York, United States
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States