Clinical Research Directory

Optimal Stimulation Parameters to Disrupt Epileptiform Activity

Sponsor: Massachusetts General Hospital

Summary

Open-loop electrical stimulation has been found to reduce spike activity and seizures, but determining the optimal parameters to achieve these effects requires a brute force trial-and-error approach that relies on subjective physician discretion. We will compare the performance of stimulation parameters identified in rodent models to the recommended parameters for neuromodulation used in clinical practice.

Official title: Optimal Stimulation Parameters for Spike-ripple Disruption in Patients Undergoing Invasive Monitoring

Key Details

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Interventions

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