Inclusion Criteria:
* Sign an informed consent form before the study and have a thorough understanding of the content, process, and potential adverse reactions of the study;
* Able to complete the study according to the requirements of the protocol;
* Subjects (including their partners) are willing to voluntarily take effective contraceptive measures within 6 months after the last study drug administration;
* Male and female subjects aged 18-55 (inclusive);
* Male subjects weighing no less than 50 kilograms and female subjects weighing no less than 45 kilograms, With a body mass index within the range of 18\~28kg/m2 (inclusive);
* Physical examination and vital signs are normal or abnormal but with no clinical significance (judged by the investigators).
Exclusion Criteria:
* Pregnant and lactating women;
* There are abnormal and clinically significant clinical laboratory examination results, or clinically significant diseases within 12 months before screening, which is not recommended to participate in the trial after evaluation by the investigators. Subjects with a previous medical history but are recovered with clinical evidence can be included in this study;
* During the screening period, any one of the vital signs, physical examination, laboratory examination, 12 lead electrocardiogram, and other auxiliary examination results is abnormal and judged by the investigator to have clinical significance;
* Subjects who test positive for any of the hepatitis B virus surface antigen (HBsAg), hepatitis C virus antibody (Anti HCV), human immunodeficiency virus antibody (Anti HIV), and Treponema pallidum antibody (Anti TP);
* Those who have undergone surgery within 4 weeks before screening or plan to undergo surgery during the study period;
* Received investigational drugs or participated in clinical trials within 3 months prior to screening;
* Received immunoglobulin or blood products within 30 days before randomization;
* Donated blood (\> 300 mL) or experienced significant blood loss (\> 400 mL) within 3 months prior to screening;
* Subjects with a history of needle sickness, blood sickness, or potential difficult in collecting blood;
* History of allergic reactions to other therapeutic monoclonal antibodies or biological agents, or history of allergies to multiple drugs or foods, especially to ingredients similar to the study drug;
* Smoking more than 5 cigarettes per day or using an equivalent amount of nicotine or nicotine containing products within 3 months before randomization, or failing to stop using any tobacco products during the trial period;
* Those who have been drinking excessively for a long time or have consumed more than 14 units of alcohol per week within 3 months before screening, or cannot abstain from alcohol during the trial period, or have tested positive for alcohol breath test;
* Subjects with a history of drug abuse, or positive urine drug screening;
* Received any commercially available or investigational biological agents within 4 months before randomization or within 5 half-lives of drugs (whichever is longer);
* Within 4 weeks before randomization, received any systemic prescription drugs, over-the-counter drugs, herbs, any vitamin products, and health products, or any topical drugs of the above forms at the injection site of this study;
* From the screening period to the study medication, acute diseases or concomitant medication occured.
* Any medical history that may affect drug absorption, distribution, metabolism, and excretion.
* Any situation that the investigator believes will pose a safety risk to the subject during the study or may interfere with the implementation of this study, or the investigator believes that the subject may not be able to complete this study or may not be able to comply with the requirements of this study.
* QT interval \> 450 milliseconds, or electrocardiogram is not suitable for Concentration-QT measurement (according to the judgment of the investigator).
* History of risk factors for torsade de pointe ventricular tachycardia. Subject with a family history of long QT syndrome or Brugada syndrome will also be excluded.
* Heart rate ≤ 45 bpm.
* History of renal or liver dysfunction.
* History or condition of cardiovascular disease.
