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A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity
Sponsor: M.D. Anderson Cancer Center
Summary
To learn about the relationship between changes in pupil size and reactivity and the start of neurological side effects in patients after receiving CAR-T cell therapy.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2024-02-08
Completion Date
2027-04-01
Last Updated
2025-10-24
Healthy Volunteers
No
Conditions
Interventions
NeurOptics® NPi®-300 Pupillometer
The pupilometer is a non-invasive device which will be placed in front of your eyes, one at a time. It looks like a handheld spotlight or scanner, with a small plastic guide sticking out that will be placed against your cheek to help keep the device in place during the scan. It will not touch your eye. Both your left and right eyes will be measured with the device each time. Scanning with the pupilometer will take less than 5 minutes total for both eyes.
Locations (1)
MD Anderson Cancer Center
Houston, Texas, United States