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RECRUITING
NCT06144151

A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity

Sponsor: M.D. Anderson Cancer Center

View on ClinicalTrials.gov

Summary

To learn about the relationship between changes in pupil size and reactivity and the start of neurological side effects in patients after receiving CAR-T cell therapy.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

100

Start Date

2024-02-08

Completion Date

2027-04-01

Last Updated

2025-10-24

Healthy Volunteers

No

Conditions

Interventions

DEVICE

NeurOptics® NPi®-300 Pupillometer

The pupilometer is a non-invasive device which will be placed in front of your eyes, one at a time. It looks like a handheld spotlight or scanner, with a small plastic guide sticking out that will be placed against your cheek to help keep the device in place during the scan. It will not touch your eye. Both your left and right eyes will be measured with the device each time. Scanning with the pupilometer will take less than 5 minutes total for both eyes.

Locations (1)

MD Anderson Cancer Center

Houston, Texas, United States