Clinical Research Directory

Inclusion Criteria: * Men or women * 35-75 years old * BMI \>27 kg/m2 * Known type 2 diabetes in stable glucose lowering therapy (for three months) or with HbA1c \>48 mmol/mol if no glucose lowering therapy Exclusion Criteria: * Anemia (hemoglobin \<8 mmol/L for men and \<7 mmol/L for women) * TSH outside reference range * Treatment with insulin, sulfonylurea, or SGLT2-inhibitors * Treatment with systemic corticosteroids * HbA1c \>70 mmol/mol * eGFR \<60 ml/min/1.73 m2 * Contraindications for MR-scan: abdominal height exceed limitations of the MR-scanner, pacemaker or other electronic device implanted, implanted metal devices, severe claustrophobia * Food allergies (including lactose and gluten intolerance) * Vegetarian/vegan diet or following of specific dietary plans * Alcohol consumptions \>84/168 g/week (women/men) * Strenuous activity level \> 120 minutes per week * Weight loss (\>5 kg) within the last three months or previous bariatric surgery * High risk of fibrosis of the liver (estimated by FIB4 score \> 3.25)