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TERMINATED
NCT06149741
NA

Defunctioning Left-sided Colostomy in Low Anterior Resection for Rectal Cancer

Sponsor: Umeå University

View on ClinicalTrials.gov

Summary

This is prospective, multi centre study evaluating a novel type of defunctioning loop stoma after low anterior resection for rectal cancer. Patients will be operated with a complete splenic flexure mobilisation and total mesorectal excision. An anastomosis will be fashioned at the pelvic floor. This will leave a redundant colon which will be brought up and matured in the left iliac fossa. Patient bowel function and quality of life will be monitored at baseline and at one year postoperatively, when the stoma will typically have been reversed. Dehydration and kidney injury are expected to become infrequent in comparison with the main alternative loop ileostomy. About 20 patients will be included in this pilot study.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

16

Start Date

2023-11-20

Completion Date

2025-07-31

Last Updated

2026-05-08

Healthy Volunteers

No

Conditions

Interventions

PROCEDURE

Defunctioning left-sided loop colostomy

Descending or left transverse double-barrelled loop colostomy in left iliac fossa after complete splenic flexure mobilisation, mesorectal excision, and anastomosis.

Locations (1)

Umeå University Hospital

Umeå, Sweden