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The Role of Histamine in Muscle Protein Synthesis Following Resistance Training
Sponsor: University Ghent
Summary
Blocking histamine H1/H2 receptors blunts chronic endurance training adaptations. The current study addresses the following research question: "What is the influence of histamine H1 signaling on training adaptations following ten weeks of resistance training in human skeletal muscle." Results from this study will yield more insights into the molecular mechanisms of adaptations to exercise training.
Official title: The Role of Histamine in Muscle Protein Synthesis Following Chronic Resistance Training
Key Details
Gender
MALE
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2023-09-01
Completion Date
2026-12-31
Last Updated
2023-12-13
Healthy Volunteers
Yes
Conditions
Interventions
Placebo
Oral placebo
H1 blockade: Telfast: 180mg Fexofenadine
H1 blockade: oral blockade with 180mg Fexofenadine
Resistance training
Resistance training: lower body exercise
Locations (1)
Department of movement and sports sciences, Ghent University, Belgium
Ghent, Oost-Vlaanderen, Belgium