Clinical Research Directory
Browse clinical research sites, groups, and studies.
Automated Titration for Home Oxygen Therapy
Sponsor: West Park Healthcare Centre
Summary
Patients with chronic respiratory disease may be prescribed oxygen therapy. Currently, the dose of oxygen flow is fixed (FixedO2) depending on activity level i.e. rest, physical activity and sleep. Automated Titration of Oxygen (AutoO2) is a closed-loop system in which the oxygen flow to the patient is continuously machine adjusted to meet the patient's immediate needs on the basis of signals from pulse oximetry (SpO2). The purpose of this study is to examine if automated oxygen control based on pulse oximetry provided to participants is superior to prescribed fixed oxygen flow in keeping SpO2 within the intended target interval of 92 to 96% arterial oxygen saturation.
Official title: Effectiveness of Automated Titration Designed for Home Oxygen Therapy
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
25
Start Date
2023-12-01
Completion Date
2026-12-31
Last Updated
2025-12-04
Healthy Volunteers
No
Conditions
Interventions
AutoO2
Automated Titration of Oxygen (Auto-O2) using a closed-loop system in which the oxygen flow to the participant is continuously adjusted on the basis of pulse oximetry signals to maintain a target range of oxygen saturation to meet the participant's immediate needs.
FixedO2
Fixed flow oxygen delivery administered using manual flow meters according to standard clinical procedures.
Locations (1)
West Park Healthcare Centre
Toronto, Ontario, Canada