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RECRUITING
NCT06153888
NA

ULtrafiltration-Rate Induced CArdiac Strain (ULRICA) - Study

Sponsor: Umeå University

View on ClinicalTrials.gov

Summary

Patients performing chronic hemodialysis (HD) retain more or less water between dialyses. The water is removed by ultrafiltration and usually during the cleansing of waste products - the HD. The length of HD is usually the same as the time of fluid removal while sometimes this may differ. There is no clear guideline. In previous research the investigator noted that the heart releases more NT-pro-BNP during HD in numerous of the patients. The present study aims to clarify if the speed of fluid removal during HD is a factor that may alter the release of cardiac markers during HD. If so the recommendations for the prescription of HD can be updated.

Official title: The Effect of Hemodialysis on proBNP

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2023-03-20

Completion Date

2026-04-30

Last Updated

2024-12-16

Healthy Volunteers

No

Interventions

PROCEDURE

Ultrafiltration rate

Fluid removal during HD will be linear. The time on HD for fluid removal is adjusted after a formula for interdialytic weight gain / removal time (see Goto et al 2023).

Locations (1)

Region Vasterbotten, Norrlands Universitetssjukhus, Dialysen

Umeå, Sweden