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ACTIVE NOT RECRUITING
NCT06159309

Quality of Life After Hyperbaric Oxygen Therapy in Post-COVID Patients

Sponsor: Rutger Lalieu

View on ClinicalTrials.gov

Summary

Post-Covid syndrome, also known as long Covid, is a clinical condition in which patients experience long term symptoms after Covid-19 infection. Treatment options for post-Covid are not effective. Therefore, there is an urgent need for a novel therapy. The first study results of HBOT in post-Covid patients are promising. Previous research from Israel has shown improvements in quality of life after HBOT. However, long term results are unknown. Therefore, this study aims to evaluate quality of life at one year after hyperbaric oxygen therapy in post-Covid patients with cognitive symptoms. It is hypothesized that quality of life at one year after HBOT is improved. Furthermore, this study aims to evaluate return to work after HBOT. To our knowledge this was not done before. An observational prospective cohort study will be conducted to answer the research questions. All post-Covid patients who are treated with hyperbaric oxygen therapy in participating centers, will be eligible for inclusion. Questionnaires and medical doctor consultations will be used in order to collect all data. There are no risks for participants, since only 7 questionnaires are not part of standard clinical care. The burden is approximately 40 minutes extra in total for participants, compared to standard clinical care.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2023-02-06

Completion Date

2025-08

Last Updated

2025-06-04

Healthy Volunteers

No

Interventions

OTHER

Hyperbaric oxygen therapy

HBOT per local protocol, i.e. 40 sessions 2.4 ATA, at the discretion of the hyperbaric physician

Locations (6)

DVK Hogeveen

Hoogeveen, Drenthe, Netherlands

DVK Geldrop

Geldrop, North Brabant, Netherlands

DVK Waalwijk

Waalwijk, North Brabant, Netherlands

HGC Rijswijk

Rijswijk, South Holland, Netherlands

DVK Rotterdam

Rotterdam, South Holland, Netherlands

DVK Amersfoort

Amersfoort, Utrecht, Netherlands