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Quality of Life After Hyperbaric Oxygen Therapy in Post-COVID Patients
Sponsor: Rutger Lalieu
Summary
Post-Covid syndrome, also known as long Covid, is a clinical condition in which patients experience long term symptoms after Covid-19 infection. Treatment options for post-Covid are not effective. Therefore, there is an urgent need for a novel therapy. The first study results of HBOT in post-Covid patients are promising. Previous research from Israel has shown improvements in quality of life after HBOT. However, long term results are unknown. Therefore, this study aims to evaluate quality of life at one year after hyperbaric oxygen therapy in post-Covid patients with cognitive symptoms. It is hypothesized that quality of life at one year after HBOT is improved. Furthermore, this study aims to evaluate return to work after HBOT. To our knowledge this was not done before. An observational prospective cohort study will be conducted to answer the research questions. All post-Covid patients who are treated with hyperbaric oxygen therapy in participating centers, will be eligible for inclusion. Questionnaires and medical doctor consultations will be used in order to collect all data. There are no risks for participants, since only 7 questionnaires are not part of standard clinical care. The burden is approximately 40 minutes extra in total for participants, compared to standard clinical care.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2023-02-06
Completion Date
2025-08
Last Updated
2025-06-04
Healthy Volunteers
No
Interventions
Hyperbaric oxygen therapy
HBOT per local protocol, i.e. 40 sessions 2.4 ATA, at the discretion of the hyperbaric physician
Locations (6)
DVK Hogeveen
Hoogeveen, Drenthe, Netherlands
DVK Geldrop
Geldrop, North Brabant, Netherlands
DVK Waalwijk
Waalwijk, North Brabant, Netherlands
HGC Rijswijk
Rijswijk, South Holland, Netherlands
DVK Rotterdam
Rotterdam, South Holland, Netherlands
DVK Amersfoort
Amersfoort, Utrecht, Netherlands