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Voice Quality Analysis of Patients With Laryngotracheal Stenosis
Sponsor: Johns Hopkins University
Summary
The investigators previously demonstrated that voice changes are common in patients with Laryngotracheal Stenosis (LTS), and patients typically report an improvement in voice outcomes following endoscopic dilation. Recently, NIH based programs such as a Bridge to Artificial Intelligence (Bridge2AI) have highlighted the use of artificial intelligence to identify acoustic biomarkers of disease. Therefore, the investigators hypothesize that progression of LTS scar can be quantified using acoustic measurements and machine learning. The goal of this clinical trial is to remotely monitor patient voice quality in an effort to determine if regularly performed voice recordings can be used as a diagnostic tool in order to predict the need for dilation procedures. The investigators feel that successful use of remote voice recording technology with algorithmic analysis will improve patient quality of life.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2026-07-01
Completion Date
2028-12-01
Last Updated
2025-08-06
Healthy Volunteers
Not specified
Conditions
Interventions
Voice Biomarker Screening Too
The investigators will develop a screening tool using voice that can predict disease severity in idiopathic subglottic stenosis
Locations (1)
Johns Hopkins Outpatient Center
Baltimore, Maryland, United States