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Use of Cinnamomum Verum for Induction of Labor. Double Blind Randomized Clinical Trial
Sponsor: Universidad Nacional Autonoma de Honduras
Summary
The purpose of the research protocol is to evaluate the effectiveness of Cinnamomum verum extract for the initiation of labor. Cinnamaldehyde ((E)-3-Phenylprop-2-enal) is an α, β unsaturated aromatic aldehyde, derived from cinnamon (Cinnamomum Verum oil) used as a flavoring; It is a clear yellowish liquid substance, with a strong odor and flavor. It is the main component of cinnamon (63%), giving it its physicochemical properties. Cinnamon has been an element of empirical use for the beginning of labor, however, its effectiveness has not been demonstrated. Cinnamon has been reported for its ethnopharmacological properties in pregnancy, being used to facilitate childbirth, as a lactagogue and for postpartum recovery. In Honduras, its use has been reported to relieve nausea and vomiting during pregnancy, to reduce abdominal pain. , reduction of lower limb edema, to relieve anxiety during labor, as well as a lactagogue without convergent opinions.
Official title: Use of Cinnamomum Verum Extract Versus Placebo for Induction of Labor and Reduction of Physiological Phase 2-3 of Labor. Double-blind Randomized Clinical Trial. CINNALAB TRIAL
Key Details
Gender
FEMALE
Age Range
14 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2023-12-04
Completion Date
2026-12-30
Last Updated
2025-12-04
Healthy Volunteers
Yes
Interventions
Cinnamomum Verum oil extract
one capsule of 1000 mg orally of Cinnamomum Verum oil extract per day for 21-28 days
Placebo
400 mg PO Canola oil soft gel capsule
Locations (1)
Hospital Escuela
Tegucigalpa, Francisco Morazán Department, Honduras