Clinical Research Directory

Inclusion Criteria: * Male or female, age 18 years or older at the time of signing informed consent * Have a BMI ≥30 kg/m2 * Have a history of at least one self-reported unsuccessful dietary effort to lose body weight For subjects with T2D at screening: * Have a diagnosis of T2D according to the WHO classification above or equal to 3 months prior to the day of screening * Treated with either diet and excercise alone or on stable treatment with up to 3 oral antidiabetic medications alone or in any combination (EXCEPT GLP-1R agonists or DPP-4 inhibitors) for at least 2 months prior to the day of screening * HbA1c 7.0-10.0% (both inclusive) at screening * Fasting blood glucose ≤11.1 mmol/L at screening Exclusion Criteria: • A self-reported change in body weight above 5% within 3 months before screening For subjects without T2D at screening: • HbA1c ≥6.5% as measured by local laboratory at screening For subjects with T2D at screening: * Have history of proliferative diabetic retinopathy, diabetic macular edema or non-proliferative diabetic retinopathy that required acute treatment * Have had 2 or more episodes of ketoacidosis, hyperosmolar state or lactic acidosis within 6 months before screening;