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Effects of Antiplatelet and Antioxidant Agents on Drusen Progression: A Pilot, Prospective Cohort Study
Sponsor: Navamindradhiraj University
Summary
The aim of this clinical trial is to evaluate the effect of low doses of antiplatelet medications (aspirin 81 mg/day or clopidogrel 75 mg/day) with or without a combination of antioxidants (N-acetylcysteine 600 mg/day) in a dry AMD patient with large drusen. Participants will divided in to three groups. * Participants who were already taking low dose antiplatelet medications. * Participants who take the antiplatelet drug mentioned above in addition to the antioxidant prescribed by the investigator * Participants does not use any medications.
Key Details
Gender
All
Age Range
50 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
174
Start Date
2023-12
Completion Date
2026-09
Last Updated
2023-12-15
Healthy Volunteers
No
Conditions
Interventions
Aspirin 81Mg Ec Tab
Patients take aspirin 81 mg per day.
Clopidogrel
Patients take clopidogrel 75 mg per day.
N-acetylcysteine
Patients are given N-acetylcysteine 600 mg per day.
Locations (1)
Department of ophthalmology, Faculty of medicine, Vajira hospital, Navamindradhiraj University
Bangkok, Dusit, Thailand