Clinical Research Directory

Inclusion Criteria: 1. In line with the diagnostic criteria of psoriasis 2. PASI\>10 or BSA\>10% 3. Understand and agree to participate in this study and sign the informed consent. Exclusion Criteria: 1. Those with serious mental diseases, such as depression, anxiety, etc; 2. PSQI\>5 points; 3. Long term use of sedative and hypnotic drugs; 4. Patients with diabetes mellitus or severe heart, liver and kidney disease; 5. Those diagnosed with sleep disorders, such as apnea syndrome, periodic limb movement disorder, restless legs syndrome, narcolepsy, etc; 6. There are serious cardiovascular and cerebrovascular diseases, respiratory system diseases, and immune system diseases; 7. Pregnant women during pregnancy, lactation, or planned trials; 8. Those who have participated in other clinical studies or are participating in other clinical trials within 3 months; 9. Unable to cooperate with the study for any reason, such as the following situation: language understanding, unable to complete the scale tester. If any one of the above items is met, it shall be excluded.