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RECRUITING
NCT06167057
NA

POST URS Chemotherapy Instillation

Sponsor: Carmel Medical Center

View on ClinicalTrials.gov

Summary

The goal of this study is to evaluate the safety and oncological outcomes of single chemotherapy bladder instillation following endoscopic treatment for UTUC in UTUC suspected patients .The main aim is to determine the efficacy of a single, post URS, chemotherapy bladder instillation to reduce IVR. Participants will be given single chemotherapy bladder instillation within 24h following ureteroscopy and will follow routine follow-up for IVR which will include white light cystoscopy ;patients with suspected IVR (based on either imaging or cystoscopy) will undergo TURBT.

Official title: Single Bladder Instillation With Chemotherapy Following Endoscopic Treatment for Upper Tract Urothelial Carcinoma to Reduce Bladder Recurrence

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

264

Start Date

2023-04-17

Completion Date

2028-01-30

Last Updated

2023-12-20

Healthy Volunteers

No

Conditions

Interventions

DRUG

Mitomycin/Gemcitabine

UTUC treatment

DRUG

Saline

UTUC treatment

Locations (10)

Assuta Ashdod Hospital

Ashdod, Israel

Soroka University Medical Center

Beersheba, Israel

Shamir Medical Center

Be’er Ya‘aqov, Israel

Bnai Zion Medical Center

Haifa, Israel

Carmel Medical Center

Haifa, Israel

Rambam Health Care Campus

Haifa, Israel

Rabin Medical Center - Beilinson and Hasharon

Petah Tikva, Israel

Kaplan Medical Center

Rehovot, Israel

Ziv Medical Center

Safed, Israel

Tel Aviv Sourasky Medical Center - Ichilov

Tel Aviv, Israel