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POST URS Chemotherapy Instillation
Sponsor: Carmel Medical Center
Summary
The goal of this study is to evaluate the safety and oncological outcomes of single chemotherapy bladder instillation following endoscopic treatment for UTUC in UTUC suspected patients .The main aim is to determine the efficacy of a single, post URS, chemotherapy bladder instillation to reduce IVR. Participants will be given single chemotherapy bladder instillation within 24h following ureteroscopy and will follow routine follow-up for IVR which will include white light cystoscopy ;patients with suspected IVR (based on either imaging or cystoscopy) will undergo TURBT.
Official title: Single Bladder Instillation With Chemotherapy Following Endoscopic Treatment for Upper Tract Urothelial Carcinoma to Reduce Bladder Recurrence
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
264
Start Date
2023-04-17
Completion Date
2028-01-30
Last Updated
2023-12-20
Healthy Volunteers
No
Conditions
Interventions
Mitomycin/Gemcitabine
UTUC treatment
Saline
UTUC treatment
Locations (10)
Assuta Ashdod Hospital
Ashdod, Israel
Soroka University Medical Center
Beersheba, Israel
Shamir Medical Center
Be’er Ya‘aqov, Israel
Bnai Zion Medical Center
Haifa, Israel
Carmel Medical Center
Haifa, Israel
Rambam Health Care Campus
Haifa, Israel
Rabin Medical Center - Beilinson and Hasharon
Petah Tikva, Israel
Kaplan Medical Center
Rehovot, Israel
Ziv Medical Center
Safed, Israel
Tel Aviv Sourasky Medical Center - Ichilov
Tel Aviv, Israel