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RECRUITING
NCT06167109
NA

NBI Combined With MRI to Guide CTV Optimization in Eccentric Nasopharyngeal Carcinoma

Sponsor: Chongqing University Cancer Hospital

View on ClinicalTrials.gov

Summary

This is a prospective, single-center clinical trial in eccentric nasopharyngeal carcinoma (NPC) patients. The aim of this study is to evaluate the efficacy and safety of NBI combined with MRI-guided optimized CTV compared with conventional CTV, and to compare the radiotherapy-related adverse events and quality of life between the two groups.

Official title: Endoscopic NBI Combined With MRI to Guide the Optimization of Clinical Target Volume Delineation in Eccentric Nasopharyngeal Carcinoma

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2023-10-20

Completion Date

2026-10

Last Updated

2023-12-12

Healthy Volunteers

No

Interventions

RADIATION

CTV optimized IMRT

The contralateral CTV1 was defined as a subclinical disease consisting of 5mm margin surrounding GTVnx.The CTV2 was defined as a potentially involved regions consisting of 5mm margin surrounding CTV1, and contralateral CTV2 only included the pharyngeal recess.

Locations (1)

Chongqing University Cancer Hospital

Chongqing, Chongqing Municipality, China