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RECRUITING
NCT06174233

The French Gut-colo

Sponsor: Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

View on ClinicalTrials.gov

Summary

Colorectal cancer (CRC) is the second most common type of cancer worldwide. The European Union recommends national CRC screening for people aged between 50 and 74. Generally, an immunological test called FIT (Fecal Immunochemical Test), based on the quantitative detection of human haemoglobin, is performed on a stool sample. If the haemoglobin level is above the recommended threshold, a colonoscopy is recommended to detect colorectal lesions. Recent studies have identified potential microbiota signatures associated with colon cancer. In this study, we will analyze the microbiota of a population aged 50 to 75 years undergoing colonoscopy as part of routine care in order to confirm the presence of microbiota signatures associated with the presence of adenomas, advanced adenomas and CRC.

Official title: "Contribution of Metagenomic Analysis of Faecal Microbiota Combined With Artificial Intelligence for the Prediction of Colorectal Cancer Risk; Study in Patients Scheduled for Colonoscopy".

Key Details

Gender

All

Age Range

50 Years - 75 Years

Study Type

OBSERVATIONAL

Enrollment

2500

Start Date

2024-06-26

Completion Date

2028-06-25

Last Updated

2025-09-16

Healthy Volunteers

Yes

Locations (1)

Hopital Avicenne, Centre de Recherche sur Volontaire

Bobigny, France