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The French Gut-colo
Sponsor: Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Summary
Colorectal cancer (CRC) is the second most common type of cancer worldwide. The European Union recommends national CRC screening for people aged between 50 and 74. Generally, an immunological test called FIT (Fecal Immunochemical Test), based on the quantitative detection of human haemoglobin, is performed on a stool sample. If the haemoglobin level is above the recommended threshold, a colonoscopy is recommended to detect colorectal lesions. Recent studies have identified potential microbiota signatures associated with colon cancer. In this study, we will analyze the microbiota of a population aged 50 to 75 years undergoing colonoscopy as part of routine care in order to confirm the presence of microbiota signatures associated with the presence of adenomas, advanced adenomas and CRC.
Official title: "Contribution of Metagenomic Analysis of Faecal Microbiota Combined With Artificial Intelligence for the Prediction of Colorectal Cancer Risk; Study in Patients Scheduled for Colonoscopy".
Key Details
Gender
All
Age Range
50 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
2500
Start Date
2024-06-26
Completion Date
2028-06-25
Last Updated
2025-09-16
Healthy Volunteers
Yes
Locations (1)
Hopital Avicenne, Centre de Recherche sur Volontaire
Bobigny, France