Clinical Research Directory

Inclusion Criteria: * BMI 30.0 - 50.0 kg/m2 * Able to attend study intervention classes and study visits/assessments * Independently living with access to food preparation facilities Exclusion Criteria: * Current smoker or regular use of nicotine containing products and/or cannabis * Heavy alcohol use (≥2 drinks/d for females, ≥3 drinks/d for males) or drug use * Known cognitive impairments or h/o stroke * Type 2 diabetes (known diagnosis or by screening A1c (≥6.5%)) * Medical conditions (chronic diseases, cancer, MS) or labs limiting ability to participate * Females: currently pregnant (or 6-months postpartum of full-term pregnancy) and/or current breastfeeding * Use of medications with significant effects on appetite (e.g., weight loss medications, atypical antipsychotics, stimulants) and/or chronic use of anticoagulants * History of bariatric surgery * History of eating disorder * Current participation in a formal weight loss program * Prior or current participation in a research study involving weight loss * Weight-reduced by \>10% within past year * Weight \> 330 pounds (MRI limit) * Allergy or intolerance to or unwillingness to consume study foods provided at visit * MRI contraindication (e.g., implanted metal, claustrophobia) * Do not have a phone compatible with activity tracker or access to videoconferencing platform that will be used for the dietary intervention or other appropriate technology needed to complete study procedures * Any condition(s) found by the study team and confirmed with the PI(s) that make it unsafe to participate