Clinical Research Directory

Inclusion Criteria: * "Red flags" include any one of the following: Clinical "Red flags": * Bilateral carpal tunnel syndrome (30). * "Popeye sign", rupture of long head of the biceps tendon. * Lumbar spinal canal stenosis in association with unilateral carpal tunnel syndrome (31). Echocardiographic/imaging "Red Flags" * LV wall thickness ≥ 12 mm and heart failure in men \> 60 y/ women \> 70y. * LV wall thickness ≥ 12 mm and AV-Block or pacemaker. * Infiltrative phenotype (biventricular hypertrophy, thickening of cardiac valves, pericardial effusion, thickening of the interatrial septum). * LV wall thickness ≥ 12 mm and low voltage on ECG. * Paradoxical low flow/low gradient aortic stenosis. Exclusion Criteria: \- 1. Patient who refuse to give a consent to the following investigations. 2. Patient with any contra-indication to undergo CMR, or bone scintigraphy will be excluded e.g., non compatible implantable cardiac devices, claustrophobic, severe kidney function impairment. 3\. Patient with established diagnosis of other infiltrative cardiac disease.