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RECRUITING
NCT06179212

Exercise Testing Protocols for Females and Males With CAD

Sponsor: Ottawa Heart Institute Research Corporation

View on ClinicalTrials.gov

Summary

The aim of this study is to determine if the test that allows males to achieve a higher VO2 (a measure of oxygen use during exercise) is different for females. The purpose of this study is to test 4 different exercise testing protocols to compare measured oxygen consumption in females and males with CAD (disease caused by the buildup of plaque in the artery walls which can lead to insufficient amounts of blood, nutrients and oxygen being supplied to the heart). The 4 exercise tests that will be completed on the treadmill are the modified Balke, modified Bruce, modified Naughton and University of Ottawa Heart Institute Slow Ramp protocols. Each test has a different stage duration (the amount of time that the test remains at a pre-determined speed and incline), and incremental increase in speed and incline. The main purpose of this study is to compare VO2 peak (the maximal amount of oxygen utilized during the exercise test) of females and males with CAD in 4 different exercise protocols. For example, the investigators will find out: 1. which exercise protocol is more likely to achieve a higher peak V̇O2 in females and which protocol is more likely to achieve a higher peak V̇O2 in males, 2. if enjoyment affects the duration of the test, and 3. how different exercise test protocols will provide different results of maximal oxygen used by the participant's body during the exercise test.

Official title: Comparing VO2 Peak Values of Exercise Testing Protocols for Females and Males With CAD

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

54

Start Date

2024-03-01

Completion Date

2030-12

Last Updated

2026-03-12

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Exercise Tests

Patients will complete 4 different cardiopulmonary exercise tests in random order.

Locations (1)

University of Ottawa Heart Institute

Ottawa, Ontario, Canada