Clinical Research Directory

Inclusion Criteria: * Participants with or without lipedema * Age range = 18-80 years * Participants with lipedema have a formal diagnosis by a physician using criteria in Appendix A of protocol * Female Exclusion Criteria: Volunteers in the lipedema or control group will be excluded with the following: * Pregnant or breast-feeding * Taking any anticoagulation or antiplatelet therapy other than aspirin (up to 100 mg daily) * Active infection anywhere in the body, or open wound on the lower-extremities or at locations for ultrasound, bioimpedance, and tissue dielectric measurements * Battery-operated device implanted that cannot be removed for ultrasound, DXA scan, bioimpedance, and tissue dielectric measurements * Primary lymphedema * Uncontrolled diabetes, renal disease, thyroid disease, or hypertension * Hormone dysregulation or another significant clinical condition affecting hormone status as confirmed by clinical co-investigators * Bone metastases * Contrast imaging scan in the previous 7 days * Nuclear medicine scan in previous 3 days * Lumbar spine fusion * Weigh more than 500 lb (226.8 kg) Also excluded are subjects incapable of giving informed written consent: * Subjects who have an inability to communicate with the researcher for any reason * Subjects who are non-English speaking who cannot communicate through a translator, or if a translator is not available * Subjects who cannot adhere to the experimental protocols for any reason * Subjects who have limited mental ability to give informed consent due to mental disability, confusion, or psychiatric disorders * Prisoners