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Auditory Prediction and Error Evaluation in the Speech of Individuals Who Stutter
Sponsor: Arizona State University
Summary
Stuttering negatively impacts communication and reduces the overall quality of life and well-being of individuals who stutter. This study will provide a strong foundation for developing neural and behavioral interventions for stuttering. Participants will be asked to name pictures, read words/sentences silently or aloud, and listen to speech and nonspeech sounds while their speech, muscle, and brain signals are collected. Some participants may also receive brain stimulation while reading and speaking.
Key Details
Gender
All
Age Range
3 Years - Any
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2024-01-01
Completion Date
2027-12-30
Last Updated
2025-08-21
Healthy Volunteers
Yes
Interventions
Delaying speech initiation
This intervention will examine the effects of misalignment between prediction and auditory feedback in participants. We will use transcranial magnetic stimulation to induce a temporal misalignment between prediction and auditory feedback while participants produce speech.
Auditory errors and pre-speech auditory modulation
This intervention will examine the contributions of auditory errors to pre-speech auditory modulation. Participants will receive auditory perturbations while speaking, and we will collect their brain activities throughout the study.
Contributions of the speech premotor cortex to pre-speech auditory modulation
This intervention will examine the effects of stimulation of the left ventral premotor cortex on pre-speech auditory modulation. Participants will receive electrical stimulation while speaking.
Delaying auditory feedback
This intervention will examine the effects of misalignment between prediction and auditory feedback in participants. We will use delayed auditory feedback to induce a temporal misalignment between prediction and auditory feedback while participants produce speech.
Locations (2)
Arizona State University
Tempe, Arizona, United States
Univeristy of Washington
Seattle, Washington, United States