Clinical Research Directory

Inclusion Criteria: 1. Are ≥18 years old 2. Are newly intubated for less than 48 hours and for reasons other than suspected bacterial pneumonia or suspected acute bacterial infection 3. Are expected to require intubation for at least 48 hours, per the discretion of the treating clinician 4. Are able to provide protocol-accepted consent (legally authorized representative \[LAR\] is acceptable) 5. Are expected to live long enough to receive a VAP diagnosis, at the discretion of the treating clinician 6. Are able to provide study-required biological samples Exclusion Criteria: 1. Have a witnessed or suspected aspiration event prompting the need for current, new intubation 2. Have known active lung cancer or metastatic disease to a lung 3. Received a lung transplant 4. Have cystic fibrosis 5. Are receiving comfort care 6. Are receiving antibiotic treatment for suspected or proven active acute bacterial infection (eg, pneumonia, tracheobronchitis, sepsis) 7. Have a current or within-the-last-30-days diagnosis of active bacterial pneumonia 8. Were previously enrolled in this trial 9. Require long-term ventilator support 10. Have a tracheostomy tube in place 11. Are currently participating in an interventional drug or device study.