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RECRUITING
NCT06182969
PHASE1/PHASE2

A Study of APG-2575 in Patients With Mild-to-moderate Systemic Lupus Erythematosus.

Sponsor: Ascentage Pharma Group Inc.

View on ClinicalTrials.gov

Summary

To evaluate the safety, tolerability, pharmacokinetics and pharmacokinetics of multi-dose APG-2575 in mild-to-moderate systemic lupus erythematosus (SLE).

Official title: A Randomized, Double-blind, Placebo-controlled Phase I/II Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of APG-2575 in Patients With Mild-to-moderate Systemic Lupus Erythematosus.

Key Details

Gender

FEMALE

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2024-08-09

Completion Date

2026-12

Last Updated

2025-12-16

Healthy Volunteers

No

Conditions

Interventions

DRUG

APG-2575

Take orally once daily (QD) for 12 weeks.

OTHER

Placebo

Take orally once daily (QD) for 12 weeks.

Locations (1)

Renji Hospital Shanghai Jiaotong University School of Medical

Shanghai, Shanghai Municipality, China