Clinical Research Directory

Inclusion Criteria: 1. Presence of cerebral ischemic embolism within the first 6 hours 2. ASA 1-4 3. Body mass index below 30 kg m-2 4. NIHSS score ≥ 10 5. Presence of isolated/combined occlusion at any level of the anterior circulation internal carotid or middle cerebral artery Exclusion Criteria: * Chronic renal failure * EF less than 40 * Presence of intracranial hemorrhage * Previous known history of severe neurological disease * Presence of bleeding diathesis * Pre-procedure GCS ≤ 8 and intubated patients * Failure to clearly show the site of vascular occlusion on diagnostic imaging results * Clinical or imaging evidence of vascular occlusion that is not internal carotid artery or middle cerebral artery * Absence of gag reflex, loss of airway protective reflex, inadequate saliva swallowing * History of lung infection, advanced COPD or respiratory failure * Known history of aspiration due to vomiting, * Known history of difficult airway * In the presence of known intolerance or allergy to certain drugs for sedation, analgesia or both * Previously known carotid artery stenosis * Pregnant patients * Patients without consent