Clinical Research Directory

Inclusion Criteria: * Adult (age \> 18 years) emergency department patient * History of sickle cell disease * Presenting to the emergency department due to acute pain related to sickle cell disease thought to be due to vaso-occlusive crisis Exclusion Criteria: * Prior enrollment in this study * Presenting with a chief complaint suggestive of a complicated crisis (such as concern for acute chest syndrome, splenic sequestration, hepatic sequestration, pulmonary embolism) as determined by the clinical care provider * Not being treated with intravenous opioids for the vaso-occlusive crisis * Patients who lack the capacity to provide informed consent * Medical history of seizures or known intolerance to virtual reality * Disabilities like vision and hearing defects etc. that preclude the use of a head mounted virtual reality device. * Known to be pregnant * Incarcerated at the time of evaluation * Over the age of 89 years old