Clinical Research Directory

Inclusion Criteria: * Patients aged between 18 and 80, * Patient who has read and signed the consent form for participation in the study after a reflection period (approximately 15 minutes). * Patient applying for outpatient hand surgery under LRA, such as upper limb trunk blocks (flexor teno synovectomy or endoscopic carpal tunnel surgery). * Patient requiring sedation associated with locoregional anaesthesia Exclusion Criteria: * Contraindication to locoregional anaesthesia or to one of the sedatives used in the protocol * Pregnant or breastfeeding patient or woman of childbearing age without highly effective contraception for the duration of the study (surgically sterile, intrauterine device (\> 14 days), hormonal contraception (same dose and formulation for at least 6 months), sexual abstinence. Women of childbearing age, i.e. fertile, are considered to be women after menarche and until they become post-menopausal, unless they are permanently infertile or have undergone surgical sterilisation. A post-menopausal state is defined as the absence of menstruation for 12 months without any other medical cause. * Patient under court protection, guardianship or curatorship * Patient not affiliated to the French social security system * Patients unable to understand informed information and/or give written informed consent: dementia, psychosis, disturbed consciousness, non-French-speaking patients, etc.