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Hypertension Explored in Long-term Postpartum Follow-up in Later Life
Sponsor: University of Oxford
Summary
The purpose of this study is to understand more about why women who have had hypertensive pregnancies may be at increased risk of high blood pressure and why these women are often at increased risk of heart and blood vessel disease later in life.
Official title: Hypertension Explored in Long-term Postpartum Follow-up in Later Life (HELPFUL)
Key Details
Gender
FEMALE
Age Range
30 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2023-03-23
Completion Date
2042-11-01
Last Updated
2024-01-02
Healthy Volunteers
No
Interventions
Hypertensive pregnancy
Participants will attend one visit lasting approximately 3-4 hours on a single day or split over multiple visits to complete all measures. Participants will first be asked to provide written informed consent for the study. Participants' anthropometric measures (waist-to-hip ratio, height and weight, hip and waist circumference and left arm circumference and resting blood pressures will then be taken. After this, the participants will undergo cardiopulmonary exercise testing, followed by magnetic resonance imaging, echocardiography, retinal imaging and vascular imaging of the ear. The study visit will conclude with participants being provided with a wrist-worn physical activity monitor to wear for 7-9 days following the visit. These monitors will provide objective measures of physical activity while people go about their normal activities.
Locations (1)
University of Oxford Department of Cardiovascular Medicine
Oxford, United Kingdom