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ACTIVE NOT RECRUITING
NCT06187103
NA

Evaluation of Improved Onboard Patient Imaging

Sponsor: Varian, a Siemens Healthineers Company

View on ClinicalTrials.gov

Summary

The primary objective of radiation therapy is to deliver a therapeutic dose of radiation precisely to the target while minimizing exposure to healthy surrounding tissues. Image-guided radiation therapy (IGRT) involves acquiring cone beam computed tomography (CBCT) scans just before or during treatment sessions. By comparing the CBCT images with the reference images from the treatment planning process, clinicians can make necessary adjustments to ensure precise targeting and account for any changes that may have occurred since the initial planning. Conventional CBCT technology is, however, limited by several factors including long acquisition times that result in motion artifacts in the image, smaller fields of view that limit the volume of anatomy that can be imaged, poor image quality that limits soft tissue visibility, and artifacts created by dense metal implants. This study will evaluate a novel CBCT imaging solution ("HyperSight") that has the potential to address the challenges of conventional CBCT.

Official title: Evaluation of Improved Onboard Patient Imaging With the HyperSight Platform on TrueBeam 4.1

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2024-07-10

Completion Date

2026-12

Last Updated

2025-12-17

Healthy Volunteers

No

Interventions

DEVICE

HyperSight Imaging

Patients receive standard of care radiation treatment on a Varian TrueBeam system equipped with HyperSight CBCT imaging. Images acquired for daily patient positioning from two different treatment fractions - typically one near the beginning of the treatment course and one at about the halfway point - will be analyzed for the study.

Locations (1)

University of Maryland Medical Center

Baltimore, Maryland, United States