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Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients
Sponsor: The Institute of Molecular and Translational Medicine, Czech Republic
Summary
Mechanically ventilated intensive care patients will be sampled for a small amount of exhaled breath condensate from the ventilator circuit and for venous blood. Proteomic analysis of the exhaled breath condensate will be performed using mass spectrometry and in the blood sample, corresponding changes in the DNA, RNA, proteins, and metabolites will be studied. Resulting profiles will be correlated with routinely monitored parameters in order to identify patterns corresponding to various pathologies in order to enable their early detection.
Official title: Proteomic Analysis of Exhaled Breath Condensate in Mechanically Ventilated Intensive Care Patients
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2026-03-01
Completion Date
2029-12-31
Last Updated
2026-03-23
Healthy Volunteers
No
Interventions
Proteomic analysis of exhaled breath condensate
Mechanically ventilated intensive care patients will be sampled for exhaled breath condensate from the ventilator circuit.
Locations (2)
Institute of Molecular and Translational Medicine, Palacky University
Olomouc, Czechia
University Hospital Olomouc
Olomouc, Czechia