Clinical Research Directory

Inclusion Criteria: Patients eligible for inclusion in this study have to fulfill all of the following criteria at enrollment: * Male and female patients with ≥18 years of age; * Patients with metastatic colorectal cancer confirmed by histopathology; * Be willing to use reliable contraceptive methods and refrain from sperm donation throughout the study period and within 3 months after the last dose; * Voluntarily join the study and provide written informed consent to participate in the study; * Have traceable medical history during the treatment; * Doctor believe the patients can benefit from the study. Exclusion Criteria: Patients fulfilling any of the following criteria at enrollment are not eligible for inclusion in this study: * Failure to sign informed consent; * Patients with contraindications to Trifluridine/Tipiracil; * Female subjects who have a positive pregnancy test or are breastfeeding; * Any medical or psychological condition in the treating physician's opinion which may prevent the patient from the study participation.