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RECRUITING
NCT06198842
PHASE2

Low Dose Treosulfan Based Conditioning Regimen and PTCy in HSCT for Nijmegen Breakage Syndrome

Sponsor: Federal Research Institute of Pediatric Hematology, Oncology and Immunology

View on ClinicalTrials.gov

Summary

The aim of the current study is to evaluate the safety and efficacy of low dose treosulfan based conditioning regimen in HSCT with post-transplant cyclophosphamide in Nijmegen breakage syndrome

Official title: Clinical Open-label Phase 2 Study of Low Dose Treosulfan Based Conditioning Regimen Efficacy in Hematopoietic Stem Cell Transplantation With Post-transplant Cyclophosphamide for Children Nijmegen Breakage Syndrome

Key Details

Gender

All

Age Range

3 Months - 21 Years

Study Type

INTERVENTIONAL

Enrollment

10

Start Date

2023-11-22

Completion Date

2029-01-31

Last Updated

2024-01-10

Healthy Volunteers

No

Interventions

DRUG

Treosulfan

Treosulfan 21mg/m2 (days -6, -5, -4)

Locations (1)

HSCT department

Moscow, Russia