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Low-intensity Physical-cognitive Exercise and Cognitive Function
Sponsor: Chiang Mai University
Summary
This study aims to examine the effects of low-intensity, combined physical-cognitive exercise on cognitive function of older people with mild cognitive impairment (MCI) and identify the mechanisms by which this exercise protocol exerts cognitive function. Older adults with MCI will be recruited to either an exercise or a control group. Low-intensity, combined physical-cognitive exercise will be prescribed to the exercise group 3 times per week for 3 months while the control group will maintain their routine lifestyle. It is hypothesized that at the end of the trial, participants in the exercise group will demonstrate significant improvement in cognitive performance and circulating biomarkers compared to baseline and the control group.
Official title: Effects of Low-intensity Exercise on Cognitive Function, Blood Biomarkers, and Metabolomic Alterations of Older Adults at Risk of Developing Dementia
Key Details
Gender
All
Age Range
60 Years - Any
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2024-04-07
Completion Date
2026-03
Last Updated
2026-02-19
Healthy Volunteers
No
Conditions
Interventions
combined physical-cognitive exercise
A combined physical-cognitive exercise will be delivered in the form of exergame, where the participants move their body to interact with the game.
Locations (1)
Department of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University
Chiang Mai, Thailand