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ITGA6 Targeting NIR-II Fluorescence Image Guided Surgery
Sponsor: Institute of Automation, Chinese Academy of Sciences
Summary
In this study, the investigators will detect hepatocellular carcinoma lesions using fluoescence imaging with ITGA6 targeting probes during tumor resection surgery. The aim is to evaluate wether intraoperative fluorescence imaging targeting ITGA6 can help to improve the detction effect of hepatocellular carcinoma, and finally help the accurate surgical resection. The main purposes of this study include: 1. To raise the detection rate of hepatocellular carcinoma intraoperatively using the novel NIR-II fluorescence molecular imaging and the ITGA6 targeting probe. 2. To validate the safety and effectiveness of the proposed ITGA6 targeting probes for clinical application.
Official title: ITGA6 Targeting NIR-II Fluorescence Image Guided Surgery of HCC Patients
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2024-01-07
Completion Date
2039-12-31
Last Updated
2024-05-22
Healthy Volunteers
No
Conditions
Interventions
RD-Cy7 fluorophore
Fluorophore targeting ITGA6 that is overexpressed in HCC cells
Locations (2)
Guangdong
Guangzhou, Guangdong, China
Sichuan
Luzhou, Sichuan, China