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RECRUITING
NCT06204835
PHASE1

ITGA6 Targeting NIR-II Fluorescence Image Guided Surgery

Sponsor: Institute of Automation, Chinese Academy of Sciences

View on ClinicalTrials.gov

Summary

In this study, the investigators will detect hepatocellular carcinoma lesions using fluoescence imaging with ITGA6 targeting probes during tumor resection surgery. The aim is to evaluate wether intraoperative fluorescence imaging targeting ITGA6 can help to improve the detction effect of hepatocellular carcinoma, and finally help the accurate surgical resection. The main purposes of this study include: 1. To raise the detection rate of hepatocellular carcinoma intraoperatively using the novel NIR-II fluorescence molecular imaging and the ITGA6 targeting probe. 2. To validate the safety and effectiveness of the proposed ITGA6 targeting probes for clinical application.

Official title: ITGA6 Targeting NIR-II Fluorescence Image Guided Surgery of HCC Patients

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

90

Start Date

2024-01-07

Completion Date

2039-12-31

Last Updated

2024-05-22

Healthy Volunteers

No

Interventions

DRUG

RD-Cy7 fluorophore

Fluorophore targeting ITGA6 that is overexpressed in HCC cells

Locations (2)

Guangdong

Guangzhou, Guangdong, China

Sichuan

Luzhou, Sichuan, China