Clinical Research Directory

Inclusion Criteria: * Have a confirmed diagnosis of bilateral idiopathic Parkinson's disease * Exhibit a UPDRS subset III score of ≥ 25 while in the preoperative medication off state * Demonstrate an improvement of Parkinson's disease symptoms by ≥30% in the medication off state following a pre-operative levodopa challenge, as assessed by the UPDRS subset III score * Possess the ability to comprehend the study's demands, treatment protocols, and procedures, and provide written informed consent before undergoing any study-specific tests or procedures Exclusion Criteria: * Patients with notable psychiatric conditions, including unrelated clinically substantial depression as assessed by the investigator, will be excluded from participation.