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RECRUITING
NCT06205992

3D-MRE and 2D-MRE for Assessing Cirrhosis and Portal Hypertension

Sponsor: Shengjing Hospital

View on ClinicalTrials.gov

Summary

How to construct a novel, non-invasive, accurate, and convenient method to achieve prediction of hepatic venous pressure gradient (HVPG) is an important general problem in the management of portal hypertension in cirrhosis. We plan to compare the ability of three demensional-magnetic resonance elastography (3D-MRE) to two demensional-magnetic resonance elastography (2D-MRE) to establish a risk stratification system and perform tailored management for portal hypertension in cirrhosis.

Official title: Three-dimensional MR Elastography and Two-dimensional MR Elastography for Assessing Cirrhosis and Portal Hypertension:A Prospective Multicenter Study

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

OBSERVATIONAL

Enrollment

100

Start Date

2022-08-16

Completion Date

2026-12-01

Last Updated

2026-02-09

Healthy Volunteers

No

Interventions

DEVICE

3D-MRE

All imaging studies were performed by using a 3.0-T MRI system (Signa HDx, GE Healthcare) with an eight-channel phasedarray body coil.

DEVICE

HVPG

HVPG measurements are performed by well-trained interventional radiologists in accordance with standard operating procedures

DEVICE

2D-MRE

All imaging studies were performed by using a 3.0-T MRI system (Signa HDx, GE Healthcare) with an eight-channel phasedarray body coil.

DEVICE

HVPG

HVPG measurements are performed by well-trained interventional radiologists in accordance with standard operating procedures

Locations (1)

Shengjing Hospital of China Medical University

Shenyang, Liaoning, China