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Can Medical Cannabis Affect Opioid Use?
Sponsor: Thomas Jefferson University
Summary
The goal of this observational study is to learn how medical cannabis (MC) affects pain and the use of opioid pain medications. Participants who have chronic pain and use prescribed opioid pain medication will opt-in to using MC or not for the 3-month study. Participants who are certified in Pennsylvania will purchase specific medical cannabis products at a reduced cost from a partnering medical cannabis dispensary monthly. All participants will complete baseline, daily, and monthly assessments to observe changes across groups.
Official title: The Effect of Medical Cannabis on Opioid Use for Individuals with Chronic Pain
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
110
Start Date
2023-09-07
Completion Date
2026-01
Last Updated
2025-02-14
Healthy Volunteers
No
Conditions
Interventions
Medical Cannabis
Participants will be restricted to specific medical cannabis products from Ethos Dispensary. They will be randomized to one medical cannabis formulation (tincture or vaporization) for the duration of the study. Each month for three months, they will purchase a different composition (predominantly THC, predominantly CBD, or balanced products) of their designated formulation. The order of compositions will be randomized and double-blinded, so participants and the research team will not know which compositions of medical cannabis they are using each month.
Locations (1)
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States