Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
COMPLETED
NCT06210594
PHASE4

Staph Intervention for Effective Local Defense

Sponsor: Johns Hopkins Bloomberg School of Public Health

View on ClinicalTrials.gov

Summary

Indigenous persons experience a high burden of Staphylococcus aureus (SA) invasive disease and skin and soft tissue infections. SA carriage on the skin is factor for development of SA infections. The goal of this clinical trial is to evaluate a community-informed approach to reduce carriage of SA. Participants will be assigned to education and household supplies for prevention of SA with and without a biomedical intervention. Researchers will compare SA carriage in the two groups.

Official title: SHIELD (Staph Intervention for Effective Local Defense): An Open-label Randomized Controlled Trial to Assess Efficacy of a Sustained Intervention (Topical Antibiotics and Skin Antisepsis) to Decrease Staphylococcus Aureus Carriage in Adults

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

78

Start Date

2024-04-01

Completion Date

2025-11-14

Last Updated

2026-06-12

Healthy Volunteers

No

Interventions

COMBINATION_PRODUCT

Mupirocin + Nozin + chlorhexidine gluconate

Education/household supplies + antibiotic + antiseptic regimen

BEHAVIORAL

Education + Household supplies

Education/household supplies

Locations (1)

Whiteriver Center for Indigenous Health

Whiteriver, Arizona, United States