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Staph Intervention for Effective Local Defense
Sponsor: Johns Hopkins Bloomberg School of Public Health
Summary
Indigenous persons experience a high burden of Staphylococcus aureus (SA) invasive disease and skin and soft tissue infections. SA carriage on the skin is factor for development of SA infections. The goal of this clinical trial is to evaluate a community-informed approach to reduce carriage of SA. Participants will be assigned to education and household supplies for prevention of SA with and without a biomedical intervention. Researchers will compare SA carriage in the two groups.
Official title: SHIELD (Staph Intervention for Effective Local Defense): An Open-label Randomized Controlled Trial to Assess Efficacy of a Sustained Intervention (Topical Antibiotics and Skin Antisepsis) to Decrease Staphylococcus Aureus Carriage in Adults
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
78
Start Date
2024-04-01
Completion Date
2025-11-14
Last Updated
2026-06-12
Healthy Volunteers
No
Conditions
Interventions
Mupirocin + Nozin + chlorhexidine gluconate
Education/household supplies + antibiotic + antiseptic regimen
Education + Household supplies
Education/household supplies
Locations (1)
Whiteriver Center for Indigenous Health
Whiteriver, Arizona, United States