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Assessment of Measurable Residual Disease in Allo-HSCT Using Digital Polymerase Chain Reaction
Sponsor: Peking University People's Hospital
Summary
A research investigation into the efficacy of digital Polymerase Chain Reaction (dPCR) for monitoring measurable residual disease (MRD) during allogeneic hematopoietic stem cell transplantation, with a focus on predicting relapse in patients diagnosed with leukemia, myelodysplastic syndromes (MDS), and related hematological conditions.
Official title: Predicting Patient Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: A Comparison of Measurable Residual Disease (MRD) Assessment by Digital Polymerase Chain Reaction and Conventional MRD
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2024-01-08
Completion Date
2027-12-31
Last Updated
2024-01-18
Healthy Volunteers
No
Conditions
Interventions
Digital PCR
digital Polymerase Chain Reaction (dPCR)
Quantitative PCR
Real-time Polymerase Chain Reaction (real-time PCR)
MFC
Multicolor Flow Cytometry
Locations (1)
Peking University People's Hospital
Beijing, Beijing Municipality, China