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ACTIVE NOT RECRUITING
NCT06212297
PHASE1/PHASE2

Fellow-eye Study (FE) of LX101 in Subjects With Inherited Retinal Dystrophy

Sponsor: Innostellar Biotherapeutics Co.,Ltd

View on ClinicalTrials.gov

Summary

Up to nine subjects who have participated in the earlier LX101 clinical study, and who meet all study eligibility criteria, will receive LX101 administration in the previously uninjected, contralateral eye to evaluate the safety of bilateral, sequential subretinal administration of LX101.

Official title: A Clinical Trial to Evaluate the Safety and Efficacy of Subretinal Re-Administration of LX101 to the Contralateral Eye in Subjects With Biallelic RPE65 Mutation-associated Inherited Retinal Dystrophy

Key Details

Gender

All

Age Range

6 Years - Any

Study Type

INTERVENTIONAL

Enrollment

9

Start Date

2023-09-12

Completion Date

2029-03

Last Updated

2025-06-29

Healthy Volunteers

No

Interventions

GENETIC

LX101

Subretinal administration of LX101 to the contralateral, previously uninjected eye

Locations (1)

Shanghai General Hospital

Shanghai, Shanghai Municipality, China