Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
ACTIVE NOT RECRUITING
NCT06214897
NA

Choline to Prevent SAM in Children With MAM

Sponsor: Washington University School of Medicine

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to test choline supplementation in children with moderate acute malnutrition in Malawi. The main question it aims to answer is: Will provision of RUSF with added choline (500mg/day) throughout treatment of moderate acute malnutrition (up to 12 weeks) reduce deterioration to severe acute malnutrition among 6-59 month old Malawian children compared with standard RUSF?

Official title: An Individually Randomized, Partially Blinded, Controlled Trial of Choline-containing Ready-to-use Supplementary Food (C-RUSF) for Children With Moderate Acute Malnutrition to Reduce Deterioration to Severe Acute Malnutrition Compared to Standard RUSF.

Key Details

Gender

All

Age Range

6 Months - 59 Months

Study Type

INTERVENTIONAL

Enrollment

1500

Start Date

2024-03-18

Completion Date

2026-06

Last Updated

2025-12-17

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

C-RUSF (Ready-to-use Supplemental Food with added Choline)

Ready-to-use Supplemental Food with added Choline

DIETARY_SUPPLEMENT

S-RUSF (Ready-to-use Supplemental Food without added Choline)

Standard Ready-to-use Supplemental Food

Locations (10)

Chikonde Health Center

Chikonde, Malawi

Chipolonga Health Center

Chipolonga, Malawi

Makhwira Health Center

Makhwira, Malawi

Mbiza Health Clinic

Mbiza, Malawi

Milonde Health Center

Milonde, Malawi

Mitondo Health Center

Mitondo, Malawi

Muloza Health Clinic

Muloza, Malawi

Namasalima Health Center

Namasalima, Malawi

Naphimba Health Center

Naphimba, Malawi

Nkhate Health Clinic

Nkhate, Malawi