Clinical Research Directory

Inclusion Criteria: * Age (18-88 years) * English speaker (written and spoken) * Temporal Mandibular Disorder (TMD) for at least 3 months * TMD Grade Chronic Pain Scale (GCPS) ≥ 0 Exclusion Criteria: * Present or past degenerative neuromuscular disease * Cardiovascular, neurological diseases, pulmonary abnormalities, kidney disease, liver disease, history of cancer within past 3 years * Cervical pain (e.g. stenosis, radiculopathy) * Any personal (or family first degree) history of mania, schizophrenia, or other psychoses * Severe psychiatric condition (e.g. schizophrenia, bipolar disorders, autism) leading to hospitalization within the last 3 years. * Use of Antipsychotics (e.g., Risperdal, Ability and clozaril)Lifetime alcohol/drug dependence or alcohol/drug abuse in past 3 months * Pregnancy or breast feeding * Color-blindness * Impaired or uncorrected hearing * Non-dominant hand * Any facial trauma that has occurred in the last 6 weeks * History of a severe facial trauma in the last 2-3 months * Conditions that would interfere with the VR mask placement (e.g. trauma, burn, infection) * Known history of severe motion sickness * Non-removable head cover, artificial hair, certain types of braids or dreadlocks * History of fainting * History of angioedema * Failed drug test (testing for opiates, cocaine, methamphetamines, and amphetamines)