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RECRUITING
NCT06214936
NA

Validating Incubators in the Lab: Optimizing Culture and Investigating blasTulation Yield

Sponsor: Reproductive Medicine Associates of New Jersey

View on ClinicalTrials.gov

Summary

The goal of this study is to determine if benchtop incubators improve the number of embryos making it to the blastocyst stage of development (about 4-6 days after fertilization) in people undergoing in vitro fertilization (IVF) treatment for their infertility. * Test the effectiveness of the benchtop incubator. * Determine if the number of embryos reaching the blastocyst stage of embryo development (the stage that the embryos are biopsied for PGT-A and frozen) is improved in the benchtop incubator compared to the box incubator. * Compare embryology outcomes between the two incubator types. * Investigate transfer and pregnancy outcomes. * Expand the knowledge surrounding the impact of the incubator on IVF outcomes. Patients will have their mature oocytes collected at the egg retrieval procedure split into two groups and randomized to be cultured in both incubator types.

Official title: The VILOCITY Trial: Validating Incubators in the Lab: Optimizing Culture and Investigating blasTulation Yield: a Randomized Control Trial (RCT)

Key Details

Gender

FEMALE

Age Range

18 Years - 41 Years

Study Type

INTERVENTIONAL

Enrollment

252

Start Date

2023-12-19

Completion Date

2026-06

Last Updated

2025-02-07

Healthy Volunteers

No

Conditions

Interventions

OTHER

Benchtop Incubator

half of the mature oocytes will be placed in the benchtop incubator and after ICSI the resulting inseminated oocytes and subsequent embryos will remain in the benchtop incubator for the remainder of embryo culture

OTHER

Box Incubator

half of the mature oocytes will be placed in the benchtop incubator and after ICSI the resulting inseminated oocytes and subsequent embryos will remain in the box incubator for the remainder of embryo culture

Locations (1)

Reproductive Medicine Associates of New Jersey

Basking Ridge, New Jersey, United States