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Validating Incubators in the Lab: Optimizing Culture and Investigating blasTulation Yield
Sponsor: Reproductive Medicine Associates of New Jersey
Summary
The goal of this study is to determine if benchtop incubators improve the number of embryos making it to the blastocyst stage of development (about 4-6 days after fertilization) in people undergoing in vitro fertilization (IVF) treatment for their infertility. * Test the effectiveness of the benchtop incubator. * Determine if the number of embryos reaching the blastocyst stage of embryo development (the stage that the embryos are biopsied for PGT-A and frozen) is improved in the benchtop incubator compared to the box incubator. * Compare embryology outcomes between the two incubator types. * Investigate transfer and pregnancy outcomes. * Expand the knowledge surrounding the impact of the incubator on IVF outcomes. Patients will have their mature oocytes collected at the egg retrieval procedure split into two groups and randomized to be cultured in both incubator types.
Official title: The VILOCITY Trial: Validating Incubators in the Lab: Optimizing Culture and Investigating blasTulation Yield: a Randomized Control Trial (RCT)
Key Details
Gender
FEMALE
Age Range
18 Years - 41 Years
Study Type
INTERVENTIONAL
Enrollment
252
Start Date
2023-12-19
Completion Date
2026-06
Last Updated
2025-02-07
Healthy Volunteers
No
Conditions
Interventions
Benchtop Incubator
half of the mature oocytes will be placed in the benchtop incubator and after ICSI the resulting inseminated oocytes and subsequent embryos will remain in the benchtop incubator for the remainder of embryo culture
Box Incubator
half of the mature oocytes will be placed in the benchtop incubator and after ICSI the resulting inseminated oocytes and subsequent embryos will remain in the box incubator for the remainder of embryo culture
Locations (1)
Reproductive Medicine Associates of New Jersey
Basking Ridge, New Jersey, United States